The path to "Open_reference.vi" shows that it's just a part of the Application Builder VIs (the "AB" in the path). So it's not called by any code you wrote.
Best guess is that this VI is very minimal, based on its size, and based on its name it probably just opens another VI by reference, probably opening all the VIs that need to go in your application one at a time.
As such, best guess is that one of the VIs that you are trying to build into the application is corrupted.
Try going to this folder:
C:\Users\<your user name here>\Documents\LabVIEW Data\LVInternalReports\LabVIEW\
There should be a folder under that matching the edition of LabVIEW you use. I don't know what Community edition would put there. Open that, then inside that find the folder there that matches one of the crashes. You can match the date\time or the report ID. Inside that you'll find a ZIP file, and inside that there is usually a few unhelpful DMP files but in some (not all) cases there will be a "lvlog.txt" file that contains some information about what was happening when everything crashed. Looking through that file can sometimes point towards a corrupt file.
